This present generation's counterpart of Haman or Hitler is the Iranian regime, among others.
Apropos of the group of Gentile haters who seek to destroy Jews spiritually, a present menace looms large. This hostile bunch seeks the demise of Jews - on the sly. They are the Catholic missionaries funded by America's Southern Baptists who by stealth work to "convert" Jews. By stealth - like the pig who flaunts his split hooves to onlookers and says, "Look, I'm kosher!" (when, in fact, it lacks the internal physical sign for being kosher). Obviously the Jews they bait are the ignorant ones, those weak on Torah knowledge. They have well over 300 million dollars budgeted for this cause. You already find them peddling their piddling spirituality in every large city of Israel, under some "Messianic" rubric [A theme they steal from authentic Judaism]. In the U.S. they have succeeded in persuading some 300,000 Jews to regard their human idol as a god. They succeed because these baited Jews hunger spiritually and cannot find or cannot meet Jewish representatives to satisfy their hunger. One of several missionary agencies for this duping purpose is called "Jews for Jesus" (יש''ו).
In the end, of course, the outcome will be "... and Hashem saves us from their plots". But meanwhile, because all Jews constitute one family - one big collective body - if the left arm hurts, the right arm wants to help. The best way to fight these destroyers is to teach the truth of Torah to these Jews "roaming in the dark". Torah is the glue that binds Jews to Judaism. This blog, for example, might just serve one day to attract the hungry soul of one lone Jew in some far flung corner of this world who, upon learning the truth, returns to Hashem; And by saving that one soul - I will have saved an entire world.